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Study: Obesity May Boost Prostate Cancer Risk in African-Americans

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African-American men are far more likely to develop and die of prostate cancer than males of any other race in the United States. A recent study reports findings that may help explain this disparity.

In a study published recently in JAMA Oncology, investigators analyzed data from 3,398 African-American and 22,673 non-Hispanic white men who had participated in the Selenium and Vitamin E Cancer Prevention Trial (SELECT). The analysis revealed that African-American men were more likely to have a body mass index (BMI) of 30 or higher, indicating obesity.

When the researchers compared African-Americans and whites with a normal BMI of 25 or less, they found the former were 28 percent more likely to have prostate cancer. Among men with a BMI of 35 or higher, African-Americans were 103 percent more likely than whites to be diagnosed with prostate cancer. Both African-American and white men with a BMI of 35 or higher were more likely to have high-grade cancer than men with a BMI of 25 or lower—81 percent and 33 percent, respectively. Obesity was associated with a 122 percent increased risk of low-grade prostate cancer in obese African-American men; their white counterparts had a 20 percent reduced risk.

These findings don’t prove that obesity is responsible for the racial disparity in prostate cancer risk, but they offer further impetus for African-American men to lose weight and keep it off.



Posted in Prostate Disorders on April 21, 2016

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