Sign Up For FREE
Health After 50 Alerts!

We value your privacy and will never rent your email address

Health After 50

Artificial Sweeteners: What You Need to Know If You Have Diabetes

Comments (0)

Americans consume a lot of sugar—to the tune of about 130 pounds per person each year when you add up all the sweet products we consume, including table sugar and high-fructose corn syrup in processed foods. While a bit of this ubiquitous flavor booster isn’t completely off limits if you have diabetes, eating and drinking too much sugar can cause you to pack on unwanted extra pounds and sabotage your efforts to keep your blood glucose under control.

With that in mind, choosing foods and beverages made with no- and low-calorie sugar substitutes may seem like a guilt-free way to satisfy a sweet tooth. But questions have long lingered about these alternative sweeteners. Are they safe? Can they help manage your weight? And how do they affect blood glucose?

The U.S. Food and Drug Administration (FDA) calls these various products “high-intensity sweeteners,” and they can be up to 20,000 times sweeter than sugar. Because of their intense sweetness, sugar substitutes can be used in small amounts, and as a result, they contribute few calories when added to foods (and some contain no calories at all). Sugar alcohols are a less intensely sweet alternative to sugar.

Safety record

Over the years, concerns about the safety of sugar substitutes have surfaced periodically. While some people should avoid or limit consumption of certain alternative sweeteners, products available for sale in the U.S. meet the FDA’s safety standards. These products include:

• Saccharin (brand names include Sweet ’N Low, Necta Sweet and others). Studies in the early 1970s found that lab rats fed saccharin developed bladder cancer, and packages warned about cancer concerns. But 30 subse- quent studies in humans failed to show that saccharin raises the risk for any cancer, and the warning labels have been removed.

• Aspartame (NutraSweet, Equal). This popular tabletop sweetener can also be found in processed foods, such as some cereals and beverages. Aspartame has been extensively studied and deemed safe, though it should be avoided by people with phenylketonuria, a rare condition that causes people to be unable to properly metabolize the sweetener.

• Sucralose (Splenda). Another common tabletop sweetener, sucralose is also widely used in food processing and can be found in products such as some desserts and beverages. According to the FDA, more than one hundred studies have demonstrated the sweetener’s safety.

• Stevia. Derived from a plant that grows in South America, stevia (Truvia) has become very popular in recent years. The FDA allows products containing a highly purified derivative of stevia to be sold as sweeteners in the United States. However, products containing whole leaf or extract of stevia are not permitted to be marketed as sugar substitutes due to concerns about how these products affect control of blood sugar, as well as their effects on the heart, kidneys and reproductive system. While manufacturers promote stevia as a “natural” sweetener, solid evidence to support claims that it’s healthier than other sugar substitutes is lacking.

• Other sugar substitutes. These include products such as acesulfame potassium (Sweet One), neotame (Newtame) and a new sweetener, advantame; all have been reviewed and approved by the FDA.

Effect on blood glucose

Sugar substitutes (other than sugar alcohols) won’t raise blood glucose levels, but they don’t improve them, either; in studies lasting up to four months, people who consumed food and drinks containing substitute sweeteners showed little change in HbA1c levels and other measures of blood glucose.

Keep in mind that just because a product contains a sugar substitute, doesn’t mean it doesn’t also contain a significant amount of carbohydrates. To avoid wreaking havoc on your blood glucose level, it’s important to check the package’s “Nutrition Facts” panel—even when the product is labeled “sugar free” or “no sugar added”—to see how many carbohydrates it contains.

Effect on weight

Studies evaluating the role of no- and low-calorie foods and drinks as aids to weight loss have had mixed results. Some trials have suggested that consuming foods and drinks that contain a sugar substitute instead of high-sugar products may lower overall calorie intake. However, a few studies have shown that people who drank soda containing a sugar substitute as part of their daily diets ended up consuming a similar number of total calories as individuals who drank regular high-sugar soft drinks.

How could that happen? Research suggests that dieters who switch from sugary drinks to sugar-free versions sometimes compensate for the missing calories by consuming more food and beverages overall. In fact, some scientists believe that eating and drinking foods and beverages containing sugar substitutes can promote weight gain. According to one hypothesis, sugar alternatives block chemical signals in the body that regulate satiety, or our sense of fullness after a meal, which could leave you feeling hungry and promote overeating. Another hypothesis is that sugar substitutes rev up the desire for sweets, making high-calorie sugary treats harder to resist.

None of these ideas has been proven, however, and well-designed clinical trials are lacking. The American Diabetes Association (in a joint statement with the American Heart Association) concluded that it’s plausible that products containing no-calorie sweeteners could help induce modest weight loss when consumed instead of full-calorie products—as long as a person can resist the urge to compensate for the missing calories.

A matter of taste

If you want to include foods sweetened with sugar substitutes in your diet, moderation is a good idea, since there’s no truly long-term research on safety in humans.

Each sugar substitute tries to mimic the real thing. Choosing the one you think succeeds is strictly a matter of taste. Also, consider the alternative: Limit sweetened foods and beverages, however they’re sweetened. Opt for water or seltzer or unsweetened coffee or tea, and most of the time, choose naturally sweet fruits (but be sure to count the carbohydrates). In time, you’re likely to lose your sweet tooth—or at least become better at controlling your cravings. 


Posted in Healthy Living on April 17, 2016

Medical Disclaimer: This information is not intended to substitute for the advice of a physician. Click here for additional information: Health After 50 Disclaimer

Notify Me

Would you like us to inform you when we post new Healthy Living Health Alerts?

Post a Comment


Health After 50 Alerts registered users may post comments and share experiences here at their own discretion. We regret that questions on individual health concerns to the editors cannot be answered in this space.

The views expressed here do not constitute medical advice, and do not represent the position of Scientific American Health After 50 or Remedy Health Media, LLC, which has no responsibility for any comments posted on this site.

Post a Comment

Already a subscriber?


Forgot your password?

New to Health After 50?

Register to submit your comments.

(example: [email protected])


Forgot Password?

Caring for a Loved One with Alzheimer’s Disease:
A Guide for the Home Caregiver

Written by two world-renowned Alzheimer’s specialists -- Dr. Peter Rabins and Dr. Ann Morrison, this practical 134-page guide provides detailed advice on how to successfully manage your day-to-day responsibilities – to your patient and to yourself. Chapters include: When It’s Time to Take Away the Car Keys, Personal Care for the Dementia Patient, Dealing with Alzheimer’s Troubling Behavior Problems, Dealing with Alzheimer’s Troubling Behavior Problems, Deciding to Move a Loved One into Residential Care.

Read more or Order

Health Topic Pages