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Diabetes Medication Linked to Joint Pain

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The FDA is warning that a class of type 2 diabetes drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors may cause severe joint pain.

The drugs include sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta) and alogliptin (Nesina) taken as either a single-ingredient drug or a multi-ingredient drug combined with other diabetes medicines such as metformin.

The DPP-4 inhibitors have been associated with severe, persistent and sometimes disabling joint pain in 33 reported cases from 2006 through 2013. While the pain can start on the first day of taking medication, it can also take years before symptom onset.The good news is that joint pain typically goes away within one month of discontinuing the drug.

If youíre taking a DPP-4 inhibitor and experiencing unexplained severe joint pain, donít stop taking your medicine. Instead, contact your doctor, who can prescribe an alternative drug.†

Posted in Diabetes on January 28, 2016


Medical Disclaimer: This information is not intended to substitute for the advice of a physician. Click here for additional information: Health After 50 Disclaimer


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